Nurses spend long hours on their feet—walking hospital corridors, standing by bedsides, and responding to emergencies. The right footwear is crucial for comfort, support, and reducing foot fatigue. Nike, known for its innovative athletic shoes, offers several models that meet the specific needs of healthcare professionals. Whether you’re looking for arch support, slip-resistance, cushioning, or easy cleaning, there’s a Nike shoe that fits your shift. Below is a comparison table followed by detailed reviews to help you find the best Nike shoes for your work in healthcare.
See also:
- Best shoes for nurses
- Best shoes for male nurses
- Best Hoka shoes for nurses
- Best waterproof shoes for nurses
Comparison Table: Best Nike Shoes for Nurses
Shoe Model (Click to scroll to review) | Best For | Features for Nurses | Price |
|---|---|---|---|
Hospital Environments | Slip-resistant sole, fluid-repellent upper, elastic heel for easy on/off | ||
All-day Standing | High-cushion React foam, breathable mesh, wide base for stability | ||
Budget-Friendly Option | Lightweight, responsive cushioning, flexible rubber sole | ||
Stylish and Supportive | Iconic design, air-cushioning, solid arch and ankle support | ||
All-day comfort and responsive cushioning | Responsive ReactX foam, dual Zoom Air units, breathable mesh upper, secure midfoot fit, long-wear cushioning |
In-Depth Reviews of the Best Nike Shoes for Nurses
Nike offers more than just running shoes—they also engineer footwear suitable for those constantly on the go in healthcare settings. Below, we break down what makes each of these shoes a great choice for nurses, based on comfort, support, durability, and safety features.
Nike Air Zoom Pulse
Best for: Long shifts, slip resistance
The Nike Air Zoom Pulse was specifically engineered for medical professionals. Tested in real hospital settings, it combines Nike’s performance know-how with the specific needs of healthcare workers. Designed for long shifts that require constant movement, the Pulse features slip-resistant traction, which helps with safety on slick hospital floors. It’s also easy to clean, thanks to its coated upper, which resists spills and fluids.
The shoe’s laceless design with elastic side panels allows quick on-and-off wear, ideal for nurses juggling time-sensitive tasks. A Zoom Air unit in the heel offers responsive cushioning, while the full rubber outsole provides grip and support for those long walking and standing hours. For any nurse who has struggled with aching feet at the end of a shift, the Pulse aims to be a relief solution designed with your workflow in mind.
Its sleek design also makes it professional enough for most dress codes, while still delivering comfort. With a loyal following among nurses, this model consistently sells well online—so grab it while it’s in stock.
Specs:
Slip-resistant rubber outsole, Zoom Air cushioning, coated upper, elastic entry, laceless
Pros:
- Built specifically for nurses and doctors
- Spill-resistant and easy to clean
- Comfortable for long shifts
Cons:
- Runs slightly narrow for wide feet
- Limited color selection
Men’s version | Women’s version
Nike InfinityRN 4
Best for: Arch support, responsive cushioning
The Nike InfinityRN 4 is the latest evolution in Nike’s Infinity line, introduced in 2023 with several upgrades that make it ideal for nurses who are on their feet all day. The shoe features Nike’s new ReactX foam, which offers greater energy return and durability compared to the older React foam used in the previous Infinity models. This translates to better shock absorption during long hospital shifts and improved comfort underfoot during fast-paced work.
The shoe also boasts an improved Flyknit upper that is stretchier and more breathable, with added water resistance—ideal for spills or unpredictable workplace conditions. A wider toe box and rockered sole make walking more natural and reduce stress on the ankles, knees, and hips. The shoe’s high stack height gives it a plush feel, which is especially helpful for nurses dealing with heel pain or plantar fasciitis.
While it’s not specifically marketed as a nursing shoe, the combination of comfort, stability, and protection makes it a top-tier choice for healthcare workers. It’s also sleek and modern, available in professional colorways suitable for medical settings.
Specs:
- ReactX foam midsole
- Flyknit upper with water resistance,
- Wide toe box,
- Rockered geometry
Pros:
- Updated cushioning with better energy return
- Breathable and water-resistant upper
- Supportive for long hours and repetitive movement
Cons:
- Slightly snug fit—consider half-size up
- Premium pricing may deter budget shoppers
Men’s version | Women’s version
Nike Air Max 270
Best for: Style + comfort combo
The Nike Air Max 270 blends sporty streetwear aesthetics with all-day comfort—making it ideal for nurses who want a fashionable yet functional shoe. The standout feature is the oversized Air unit in the heel, which provides plush cushioning that absorbs shock throughout the workday. Meanwhile, the mesh upper keeps things breathable during long shifts, and the sock-like fit helps reduce friction and rubbing.
For nurses who like a bit of flair, the 270 comes in a wide variety of colors and finishes, from subtle to bold. It’s also lightweight and flexible, which helps with quick movements and constant walking. That said, it’s best for those with neutral arches, as it doesn’t provide as much corrective support as other models.
If you’re after a nurse-approved shoe that looks great outside of work, the Air Max 270 delivers style without sacrificing comfort.
Specs:
- Visible heel Air unit
- Mesh upper
- Foam forefoot
- Slip-on fit with pull tab
Pros:
- Stylish and professional
- Very cushioned heel
- Lightweight and breathable
Cons:
- Not ideal for flat feet
- Heel can feel unstable on slick floors
Men’s version | Women’s version
Nike Zoom Winflo 10
Best for: Budget-friendly support
If you’re a nurse looking for reliable support without the premium price tag, the Nike Zoom Winflo 10 is a strong contender. It’s a neutral running shoe that doubles as an excellent work shoe, especially for those who spend hours walking hospital floors. The Winflo 10 offers a good balance of comfort, cushioning, and flexibility—without the bulky profile or premium cost of some other models.
It features Zoom Air in the forefoot and Cushlon foam in the midsole, giving it a springy feel that reduces foot fatigue. The mesh upper promotes ventilation, and the padded collar and tongue add to the overall comfort. It’s especially good for nurses on a budget or for use as a second pair when rotating shoes during long shifts.
This model may not offer specialty nurse-specific features, but it ticks all the boxes for day-to-day support.
Specs:
- Zoom Air cushioning
- Cushlon foam midsole
- Engineered mesh
- Padded collar
Pros:
- Affordable without compromising comfort
- Lightweight and responsive
- Breathable construction
Cons:
- Not designed specifically for medical settings
- Slightly less traction than slip-resistant shoes
Men’s version | Women’s version
Nike Revolution 6
Best for: Budget-friendly comfort and breathability
The Nike Revolution 6 is an affordable, lightweight running shoe that doubles as a solid option for nurses who spend long hours on their feet. With a soft foam midsole and breathable mesh upper, it offers comfort and ventilation throughout demanding shifts. The shoe’s design focuses on simplicity and functionality, making it suitable for those who prioritize comfort over advanced features.
While the Revolution 6 doesn’t boast the latest Nike technologies, its straightforward construction provides adequate cushioning and support for everyday wear. The outsole’s traction pattern ensures stability on various surfaces, which is beneficial in fast-paced healthcare environments. However, individuals with wider feet might find the fit slightly snug, and those requiring specialized support may need to consider other options.
Specs:
Soft foam midsole, breathable mesh upper, rubber outsole with traction pattern, lace-up closure
Pros:
- Affordable price point
- Lightweight and breathable design
- Suitable for everyday wear
Cons:
- May run narrow for some users
- Lacks advanced cushioning technologies
- Limited arch support
Men’s version | Women’s version
Nike Pegasus 41
Best for: All-day comfort and responsive cushioning
The Nike Pegasus 41 is the latest update in Nike’s long-standing Pegasus line—beloved by runners and now a solid choice for nurses. Designed with updated ReactX foam in the midsole, this model offers enhanced energy return with improved environmental sustainability. It provides a responsive, cushioned experience that helps reduce fatigue, particularly for nurses who stand or walk for extended periods during their shifts.
The Pegasus 41 features dual Air Zoom units in both the forefoot and heel, delivering added shock absorption exactly where nurses need it most. A newly engineered mesh upper increases breathability and comfort, keeping feet cool in fast-paced, warm hospital environments. The Dynamic Midfoot Fit system creates a secure lockdown that adapts to foot movements, preventing unwanted slipping inside the shoe.
This shoe also benefits from thoughtful sustainability measures, being built with at least 20% recycled content by weight. It’s durable, well-ventilated, and designed for day-in, day-out wear. While the slightly heavier construction may not appeal to minimalists, most wearers will appreciate the balance of cushioning and support.
For nurses who want a shoe that looks sleek, lasts long, and performs across a variety of demands, the Pegasus 41 is an excellent, modern option.
Specs:
- Full-length ReactX foam midsole
- Dual Air Zoom units in forefoot and heel
- Engineered mesh upper
- Dynamic Midfoot Fit system
- Approx. 10.4 oz (men’s size 9)
- 10 mm heel-to-toe drop
- Approx. 33.6 mm stack height at heel
- At least 20% recycled material by weight
Pros:
- Enhanced energy return
- Excellent cushioning and ventilation
- Durable and supportive fit
- Sustainable construction
Cons:
- Slightly heavier than earlier models
- May need short break-in period
